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Clinical Trials/NCT05578027
NCT05578027
Completed
Not Applicable

Change in Skin Surface Temperature at the Knee Area on Both Sides When Using Mild Moxibustion Manipulation at Mingmen Acupoint With Moxa Stick: A Pilot Study

Bui Pham Minh Man1 site in 1 country38 target enrollmentStarted: October 1, 2022Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Bui Pham Minh Man
Enrollment
38
Locations
1
Primary Endpoint
Change in skin surface temperature at the local stimulated area when using mild moxibustion manipulation at Mingmen acupoint

Overview

Brief Summary

Moxibustion plays an important role in Traditional Medicine treatments, which treats and prevents diseases by burning a herb preparation containing Moxa (Artemisia vulgaris, Mugwort) to stimulate the meridians of human body. Moxibustion is considered a safe and effective traditional therapy. Mild moxibustion is a kind of therapeutic method which characterized by wide indications, simple manipulation and comfortable feeling, is commonly used in clinical treatment. Mingmen acupoint located on the midline of the lower back, in the depression below the spinous process of the 2nd lumbar vertebra (L2). Its indications include Yang-deficiency syndrome, Cold-Stagnation syndrome, Cold Excessive syndrome,... and it is closely related to the knee area through the path of Thoroughfare Vessel (one of the Eight Extraordinary Vessels). In our study, we investigate the change in skin surface temperature at the knee area on both sides when using mild moxibustion manipulation at Mingmen acupoint with moxa stick in healthy volunteers.

Detailed Description

Participants and Methods: A randomized controlled trial is conducted by comparing the change in skin surface temperature before and after using mild moxibustion manipulation at the research acupoint (Mingmen (GV-4) acupoint) or the control acupoint (the left side Pishu (BL-20) acupoint) in healthy volunteers. A total of 38 participants will undergo 2 trial phases, corresponding to 2 times of moxibustion in 8 days, each time is 7 days apart. In the first trial phase: participants received moxibustion at left side Pishu (BL-20) acupoint. In the second trial phase: participants received moxibustion at Mingmen (GV-4) acupoint. The primary outcome was the change in skin surface temperature at the local stimulated area and the knee area on both sides when using mild moxibustion manipulation at Mingmen acupoint. This trial will be performed as a pilot study.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Single Group
Primary Purpose
Basic Science
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 30 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy males and females were individual age between enough 18 and 30 years old.
  • BMI: 18.5 - 23 kg/m2
  • Mental alertness, good contact, cooperation with researchers.
  • Had no psychiatric stress problem during moxibustion day (confirmed by answering the DASS 21 questionaire with stress point less than 15 points).
  • Had no history of cardio-vascular disease, diabetes, hyperthyroidism, hypothyroidism.
  • Vital sign within normal limits:
  • Heart rates from from 60 to 99 beats/minute.
  • Systolic blood pressure between 90 and 139 mmHg.
  • Diastolic blood pressure between 60 and 89 mmHg.
  • Breathing rate: 16 ± 3 times/minute.

Exclusion Criteria

  • Having an inflammatory injury in the site of the skin to be investigated.
  • Medical history of asthma or allergy with moxa smoke.
  • Using heat therapy, for example massage, cupping therapy, acupuncture in the site of the skin to be investigated within 24 hours.
  • Applying chemical or pharmaceutical products to the site of the skin to be survey before conducting the study.
  • Other diseases that could affect or interfere with outcomes, including common cold or flu.
  • Playing sport 2 hours before the study.
  • Taking stimulants such as beer, alcohol, coffee and tobacco within 24 hours before conducting the study.
  • Skin surface temperature disorders or sensation disorders at lower-back or knee area.
  • Staying up at night or having insomnia before moxibustion day.
  • Women during menstruation period, pregnancy, or breastfeeding.

Outcomes

Primary Outcomes

Change in skin surface temperature at the local stimulated area when using mild moxibustion manipulation at Mingmen acupoint

Time Frame: During procedure

Change in skin surface temperature at the knee area on both sides when using mild moxibustion manipulation at Mingmen acupoint

Time Frame: During procedure

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Bui Pham Minh Man
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Bui Pham Minh Man

Medical Doctor

University of Medicine and Pharmacy at Ho Chi Minh City

Study Sites (1)

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