General Evaluation of Eligibility for Substance Abuse/Dependence Research
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 7,500
- 试验地点
- 1
- 主要终点
- Urine Toxicology
研究概览
简要总结
The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.
详细描述
Approximately 1500 candidates per year will respond to advertisements and will complete preliminary telephone screening without identifiers. Appropriate candidates will be given appointment times and on arrival will undergo the consent process for evaluation. A complete medical, social, psychiatric, and drug use history will be obtained. Subjects fulfilling general health inclusion requirements will then be offered an appropriate study for which the specific consent will be obtained. The evaluation period will be no more than one day with all results evaluated within the two following days. Acceptable candidates will then be invited to complete the study specific consent.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Willing and able to participate in 3- to 6-month treatment program.
- •At least 18 years of age.
- •Seeking treatment for substances of abuse including (cocaine, opiates, and alcohol).
- •Generally physically healthy.
排除标准
- •Pregnant or breastfeeding.
- •Mandated by the courts/parole officers to attend treatment.
- •Not seeking treatment for substances of abuse.
- •Plans to move from the Houston area within the 3- to 6-month treatment period.
- •Seeking treatment for a substance for which the Treatment Research Clinic (TRC) has no current trial.
研究组 & 干预措施
A
Cocaine Dependent Subjects
干预措施: modafinil (Drug)
A
Cocaine Dependent Subjects
干预措施: d-amphetamine (Drug)
A
Cocaine Dependent Subjects
干预措施: L-Dopa (Drug)
A
Cocaine Dependent Subjects
干预措施: Naltrexone (Drug)
结局指标
主要结局
Urine Toxicology
时间窗: 6 weeks to 24 weeks
次要结局
- Demographics(6 weeks to 24 weeks)
研究者
Joy Schmitz
Professor - Psy, Behavioral Science
The University of Texas Health Science Center, Houston