Physical training program and its effects on inflammatory, respiratory, quality of life, biochemical and health levels.

Not Applicable

Recruiting

• Conditions: COVID-19; post-COVID-19; non-communicable chronic diseases; communicable diseases; B97.2

• Registration Number: RBR-7z3kxjk
• Lead Sponsor: niversidade Federal de Pernambuco

Brief Summary

This research is of great importance, as it is intended to analyze the effect of an intervention based on physical exercise (supervised and at home) on immunological factors, cardiorespiratory function, intestinal microbiota and lifestyle in patients with chronic non-communicable diseases ( hypertension, obesity, diabetes, heart disease, nephrology, cancer and HIV/AIDS) who were infected with COVID-19 (SARS-CoV-2) and received medical clearance. Based on the results of this research, we seek to improve and elucidate knowledge related to the immune system, nutrition, intestinal microbiota, biochemistry and respiratory function for two years. HUIZHENG, et al and HUANG et al; 2020, report that patients with COVID-19, demonstrate a decrease in lymphocytes and increased levels of inflammatory cytokines and have diarrhea, thus we can relate the importance of this research, as it is proven that aerobic and strength physical exercise improve function and respiratory muscles, regulates and stimulates the release of cytokines, improving the inflammatory response of the body mechanism by which we fight infectious agents and modulate the intestinal microbiota, thus it is necessary and of utmost importance to carry out research involving the practice of physical exercise supervised, thus being able to elucidate new forms of rehabilitation and monitoring of patients who have already been infected with the disease. All actions of this project will clarify and develop knowledge and protocols for the improvement of infected patients acting directly in the Brazilian Public Health with measures and actions to reduce public spending on Health.

Detailed Description

Not available

Study Timeline

• Results First Posted: 2021-08-01
• Study Start: 2021-12-13
• Study Completion: 2022-12-30
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Adults; both sexes; who developed COVID-19; confirmation of COVID-19 infection; hypertensive, obese, diabetes, heart disease, nephrology, cancer and HIV/AIDS; with medical discharge and not having limitations to perform the physical fitness test and intervention protocol.

Exclusion Criteria

Individuals who did not reach the cutoff points on the Mini-Mental State Examination (MMSE); individuals with physical limitations; hospitalized in the last 12 months prior to COVID-19 infection; decompensated heart failure and chronic obstructive pulmonary disease.

Study & Design

• Study Type: Intervention
• Study Design: Not specified