Comparing the Effects of Vaginal Misoprostol, Vaginal Trinitroglycerin (TNG) and oral Evening Primrose Oil in Cervical Ripening at term pregnancy,
Phase 3
Recruiting
- Conditions
- pregnancy.
- Registration Number
- IRCT20191115045453N1
- Lead Sponsor
- Gorgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 201
Inclusion Criteria
Pregnant women (primigravid)
the term pregnancy (40 weeks onwards)
Bishop Score less or equal to 4
candidate for induction of childbirth
Exclusion Criteria
History of past uterine surgery
Use of intrauterine contraceptives (IUD)
Any medicinal allergy
Developing systemic and localized infection
Developing known diseases such as diabetes, hypertension and...
Existence of any uterine abnormalities.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cervical ripening according to Bishop Score. Timepoint: Before and after 4 hours of intervention. Method of measurement: Bishop's rating table (between 0 and 13).;Baby Apgar Score. Timepoint: Minutes One and 5. Method of measurement: Apgar Scoring System (0 to 10).;Duration of prescribing medications to childbirth. Timepoint: Time of prescription medication and delivery time. Method of measurement: Based on minutes.;Drug side effects. Timepoint: Prescribed time of medication and 4 hours after drug Administration. Method of measurement: Nausea, vomiting, vaginal bleeding, fever and chills, blurred vision, diarrhea, feeling of bitter taste in the mouth, vaginal pain.;Vaginal bleeding rate. Timepoint: Postpartum. Method of measurement: It will be measured with a scale of zero to 3 (= 0 = no bleeding, 1 = bleeding), 2 = Low menstrual bleeding, 3 = severe bleeding with clot excretion.
- Secondary Outcome Measures
Name Time Method