An Open labelled Randomised Control Trial to compare the efficacy and safety of Benzonatate and Levodropropizine in the treatment of chronic refractory cough in ILD patients

This study is a open labelled randomised control trial to compare the efficacy and safety of benzonatate and levodropropizine in treatment of chronic refractory cough in ILD ppatients . study will be conducted in AIIMS JODHPUR .Objectives of the study are to assess the efficacy of Benzonatate and Levodropropizine in treatment of chronic refractory cough in ILD Patients using Leicester Cough Questionnaire ,Cough VAS score ,To check the safety profile of Benzonatate  and Levodropropizine therapy ,to identify the factors affecting the outcome of therapy .Patient who are >18 years with diagnosed case of ILD with Cough VAS score of 

40mm if their giving consent ,will be included in the study .Pregnant and lactating woman , active smokers , severly ill patients,with the history of arrythmia and cardiac illness ,with other causes of cough ,and those who are taking any other traditional treatment remedies will be excluded from the study.ILD patient with chronic refractory cough attending pulmonary medicine OPD will be enrolled in the study ,once inclusion and exclusion criteria has fulfilled . patients will be randomised to 2 groups will be done with a computer generated sequence . One group will receive benzonatate capsule 100 mg TDS and the other group will get Levodropropizine syrup 10 ML TDS . we will compare the effectiveness with the help of various cough scores like LCQ ,Cough VAS and adverse effects will be noted.Sample size is 56 and 23 in each group .outcome will be asessed at 2 weeks and 4 weeks .