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Clinical Trials/NCT04978064
NCT04978064
Completed
Not Applicable

E-health Psychological Intervention in Pregnant Women Exposed to Intimate Partner Violence (eIPV): a Pilot Randomised Controlled Trial

Universidad de Granada2 sites in 2 countries24 target enrollmentOctober 7, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pregnancy Related
Sponsor
Universidad de Granada
Enrollment
24
Locations
2
Primary Endpoint
Consent rate for a future full-scale RCT trial
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The investigators will assess the need and feasibility of randomising a sufficiently large number of women exposed to IPV during pregnancy in a full-scale future randomised trial. To achieve this, the investigators will:

  1. estimate rates of consent to randomization, and the rates of adherence and dropout following randomization (for the use in sample size estimation)
  2. determine recruitment duration
  3. examine the women's perception about the benefit of the intervention
  4. determine the reasons for acceptability, non-adherence, and obstacles to recruitment, randomisation and consent through qualitative interviews

Detailed Description

Introduction. Intimate partner violence (IPV) during pregnancy, a condition as common as obstetrics conditions like gestational diabetes, is associated with maternal and neonatal complications. Systematic detection of IPV is not well established in antenatal screening probably because the effectiveness of protective interventions has not been evaluated. Among mothers exposed to IPV, e-health interventions during pregnancy may be beneficial. Prior to performing a full-scale effectiveness trial for such an intervention, a pilot study is required to assess the need and feasibility of randomising a sufficiently large number of women at exposed to IPV during pregnancy. Methods. The eIPV trial is a randomised pilot study nested within a cohort of consenting mothers at \<12 weeks' gestation who screen positive for IPV in the first antenatal visit and accept an e-health package (psychological counselling by videoconference) in Spain and Denmark. Twenty eligible mothers from the above cohort will be randomised to either intervention or control. The intervention group will receive the e-health package as part of the cohort. The control group will be invited to accept a delay in the intervention (e-health package eight weeks later). After consenting to delay, the control group will provide comparative data without losing the opportunity of obtaining the intervention. The investigators will determine estimates of rates of informed consent to randomization, and the rates of adherence and dropout following randomization. Qualitative interviews will be conducted to examine the women's perception about the benefit of the intervention, reasons for acceptability and non-adherence, and obstacles to recruitment, randomisation and consent. The results will inform the feasibility and variance of key clinical outcome measures for estimation of sample size of the full-scale effectiveness trial. Comment. The pilot study nested within the cohort study will allow us to obtain information about the rates of IPV in pregnancy, the acceptability of an e-health intervention and the availability of participants for randomisation into a large effectiveness trial.

Registry
clinicaltrials.gov
Start Date
October 7, 2021
End Date
November 14, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Antonella Ludmila Zapata Calvente

Principal Investigator

Universidad de Granada

Eligibility Criteria

Inclusion Criteria

  • Pregnant women at \<12 weeks gestation, who screen positive in IPV at the first antenatal visit and accept the e-health package.

Exclusion Criteria

  • Women who cannot be informed about the study without their partners or other family members knowing
  • Women mentally or physically incapacity to participate in the study
  • Women below 16 years in Spain or below 18 years in Denmark
  • Inability to understand Danish/Spanish
  • Lack of internet and electronic device
  • Women with extreme severity of IPV. Women selected to participate in the trial in this situation will receive a danger assessment before randomisation and if the severity of IPV is confirmed, they will be routinely treated and supported according to the standard protocol in each country. Women who have same-sex partners will be screened, but their data will not be used for the purpose of this study.

Outcomes

Primary Outcomes

Consent rate for a future full-scale RCT trial

Time Frame: Three to nine months

Rate of women who were positive in IPV, consent to receive e-health package and consent to randomization in the control group.

Secondary Outcomes

  • Positivity rate of the cohort study (useful for planning the future full-scale randomised control trial):(Three to nine months)
  • Completion rate in the intervention group a future full-scale RCT trial(Three to nine months)
  • Completion rate in the control group a future full-scale RCT trial(Three to nine months)
  • Recruitment duration for a future full-scale RCT trial(Three to nine months)
  • Benefit of the intervention a future full-scale RCT trial(Three to nine months)
  • Perception about the delay of the intervention of the control group for a future full-scale RCT trial(Three to nine months)
  • Reasons for acceptability, non-adherence, and obstacles for a future full-scale RCT trial(Three to nine months)
  • Follow up rate for a future full-scale RCT trial(Three to nine months)

Study Sites (2)

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