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Clinical Trials/NCT04227912
NCT04227912
Completed
Not Applicable

Comparison of Postoperative Analgesic Efficacy of Preemptive Ultrasound-guided Transversus Abdominis Plane Block, Ultrasound-guided Local Infiltration and Intravenous Dexketoprofen in Inguinal Hernia Repair

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital1 site in 1 country120 target enrollmentFebruary 11, 2019
ConditionsInguinal Hernia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Inguinal Hernia
Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Enrollment
120
Locations
1
Primary Endpoint
Postoperative rescue tramadol consumption
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study evaluates the compare the effects of ultrasound guided TAP block, local anesthetic infiltration to the incision line and intravenous dexketoprofen on postoperative analgesic efficacy and rescue tramadol consumption in inguinal hernia repairs.

Detailed Description

Currently, multimodal techniques are used in inguinal hernia repairs in addition to pharmacological and regional techniques for postoperative analgesia.TAP block is performed on the principle of hydrodissection of the fascia between the internal oblique and transversus abdominis muscles of the abdominal wall muscles with local anesthetic drugs. Local anesthetic drugs provide analgesic effect up to 24 hours in the postoperative period by blocking the T6-L1 nerves in the facial plane. Local anesthetic infiltration which is one of the regional anesthetic techniques, is another method of postoperative analgesia. intravenous analgesic drug is also used as pharmacological postoperative analgesia method in most clinics.

Registry
clinicaltrials.gov
Start Date
February 11, 2019
End Date
October 1, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Fikret Salık

Assistant Professor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • Subject who aged 18-75 years
  • American Society of Anesthesiologist (ASA) I-III
  • Subject undergoing unilateral or bilateral inguinal hernia repair

Exclusion Criteria

  • Subject under 18 and over 75 years of age
  • History of allergy to agents
  • Analgesic drug use in the last 48 hours
  • Morbid obese (BMI\> 35)
  • Confusion
  • Coagulopathy
  • Local infection at the injection site
  • Subject with heart, lung, hematologic, metabolic and endocrine disease
  • Subject who did not want to be included in the study
  • Subject who refused the spinal anesthesia

Outcomes

Primary Outcomes

Postoperative rescue tramadol consumption

Time Frame: 24 hours

The mean tramadol consumption in the first 24 post-operative hours

Secondary Outcomes

  • Postoperative nausea-vomiting(24 hours)
  • Analgesic efficacy(24 hours)

Study Sites (1)

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