Efficacy and safety of Tongxinluo capsules combined with metoprolol tartrate in the treatment of angina pectoris in coronary heart disease: A study protocol of randomized, double-blind, placebo-controlled clinical trial
Phase 1
- Registration Number
- TCTR20220505005
- Lead Sponsor
- Pengcheng Ren
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
1.meeting the diagnostic criteria for coronary angina 2. 18 to 70 years old 3.Bruce Protocol 3 to 12 min 4. patients agreed to join this study and signed the informed consent form.
Exclusion Criteria
1.patients with drug allergy in this study 2. patients with acute cardiomyopathy or congestive heart failure within 3 months 3. ALT, AST or Cr up to 1.5 times the normal upper limit 4. those with communication impairment or poor compliance 5. women who are pregnant, preparing for pregnancy or breastfeeding.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Lipid levels 12 weeks TC; TG; LDL-C; and HDL-C.
- Secondary Outcome Measures
Name Time Method Before and after treatment and at follow-up, the patients' left ventricular end-diastolic diameter (LVEDD) 12 weeks left ventricular end-systolic diameter (LVESD)