evetiracetam for Treatment of Non-psychotic and Non-depressive behavioural symptoms of dementia.
Completed
- Conditions
- 3 moths, prospective, open label trial
- Registration Number
- NL-OMON23657
- Lead Sponsor
- Dep geriatrics JBZHervensebaan 4Postbus 1101 5200 BD Den Bosch073-6998629
- Brief Summary
Dautzenberg PLJ et al. Medicamenteuze behaneling van gedrags- en psychische problemen bij dementie (BPSD). Tijdschrift voor verpleeghuisgeneeskunde 2003;27(5):5-9. Weiner MF et al. Levetiracetam for agitated Alzheimer's disease patients. Int J Psychogeriatrics 2005;17(2):327-8.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
1. Ambulant patients with dementia, level Reisberg 4-6;
2. Informant available.;
Exclusion Criteria
1. NPI item hallucinations, delusions and depression > ;1
2. Epilepsia;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect on week 4 and 13 compared to base-line on Behauvioral symptoms (NPI and CMAI), care-giver burden (CBI) and clinical impression (GCI).
- Secondary Outcome Measures
Name Time Method Effect on week 4 and 13 compared to base-line on cognition (MMSE) and ADL (IDDD).