Carotid body dysfunction in type 2 diabetes - Carotid body function in T2DM

eids Universitair Medisch Centrum0 个研究点目标入组 32 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•* Insulin dependent diabetes mellitus
•* Diagnosed Obstructive Sleep Apnea (OSAS) or high suspicion of OSAS determined
•by a STOP-BANG score > 5
•* Respiratory or cardiovascular disease
•* Smoking/vaping
•* Positive pregnancy test
•* conditions that result in elevated levels of methaemoglobinia
•* body mass index > 35 kg/m2
•* Use of illicit drugs
•* Use of prescription opioids or benzodiazepines
•* Failure of the drug of abuse tests at screening or check-in.
•* History of dyspnea, asthma, tuberculosis, chronic obstructive pulmonary
•disease, or any other ventilatory / lung disease.
•* Subjects with excessive facial hair preventing sealing of the occlusive face
•* Subjects who, in the opinion of the investigator, will not be able to
•participate optimally in the study.
•* Subject who has a history of any infectious disease within 4 weeks prior to
•drug administration that in the opinion of the investigator, affects the
•subject*s ability to participate in the trial.
•* Subjects who are part of the study staff personnel or family members of the
•study staff personnel.
•* Subjects who have demonstrated allergic reactions (e.g., food, drug, atopic
•reactions or asthmatic episodes) which, in the opinion of the investigator and
•sponsor, interfere with their ability to participate in the trial.
•* Personal or family history of arrhythmias or ECG conductance abnormalities.
•* Hypokalemia defined as <3.5 mmol/L

发起方