NL-OMON56510招募中不适用
Exercise as a countermeasure against the effects of ageing on muscle mitochondria, diffusive oxygen transport and muscle volume - Skeletal muscle mitochondria in ageing/AGAMEMNO
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •In order to be eligible to participate in this study, young sedentary
- •participants must meet all of the following criteria:
- •Aged between 18-30 years
- •Male or female
- •Not currently engaging in any formal exercise training or competitive sports
- •No chronic health conditions likely to affect exercise tolerance or the
- •physiological responses to exercise
- •In order to be eligible to participate in this study, young trained
- •participants must meet all of the following criteria:
- •Aged between 18-30 years
- •Male or female
- •Currently engaging in formal training (at least 3 times per week) in
- •competitive endurance sports
- •No chronic health conditions likely to affect exercise tolerance or the
- •physiological responses to exercise
- •In order to be eligible to participate in this study, older sedentary
- •participants must meet all of the following criteria:
- •Aged between 50-65 years
- •Male or female
- •Not currently engaging in any formal exercise training or competitive sports
- •No chronic health conditions likely to affect exercise tolerance or the
- •physiological responses to exercise
- •In order to be eligible to participate in this study, older trained
- •participants must meet all of the following criteria:
- •Aged between 50-65 years
- •Male or female
- •Currently engaging in formal training (at least 3 times per week) in
- •competitive endurance sports
- •No chronic health conditions likely to affect exercise tolerance or the
- •physiological responses to exercise
排除标准
- •Age that falls outside of 18-30 years (young groups) or 50-65 years
- •(middle-aged groups)
- •Inability to provide informed consent
- •History of claustrophobia
- •Ineligibility to perform the exercise test described in this study protocol
- •or follow instructions
- •Contraindication for MRI (e.g. pacemaker, claustrophobia; see F1
- •vragenlijsten screening MRI Amsterdam )
- •Being under investigation for non-diagnosed disease at the time of
- •investigation
- •Risk factors for exercise testing registered by a Dutch version of the
- •pre-participation questionnaire (American college of sports medicine and
- •American Heart association). Possible risk factors will be discussed with a
- •medical specialist or general practitioner before a subject can be included
- •BMI >30 due to adiposity, since this is known to cause difficulties in
- •obtaining muscle biopsies and NIRS measurements
- •Vastus lateralis adipose tissue thickness >10 mm due to difficulties in
- •obtaining high quality NIRS data
- •Pregnancy
- •Are current smokers or have been a regular smoker within the last 12 months
研究者
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