Comparison of Efficacy of Azithromycin Alone vs Combination of Azithromycin and Probiotics in Management of Mild to Moderate Acne Vulgaris
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Reduction of Acne Lesion Count as per Acne Global assessment scale
研究概览
简要总结
The Goal of this Clinical trial is to compare the efficacy of oral azithromycin alone with combination therapy of oral azithromycin and probiotics to see is there any significant difference in outcome of two treatment modalities in mild to moderate acne vulgaris
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 35 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants with mild to moderate acne on basis of global acne assessment scale score of 2 or 3 and with 20 to 50 total lesion count will be included.
排除标准
- •History of active localized or generalized infection History of autoimmune disease History of other facial skin diseases/ excessive facial hair or scars History of using isotretinoin or oral contraceptive pills in past 6 months History of already using antibiotics for acne treatment History of facial cosmetic procedures within last 3 months History of allergy to drugs used in study History of using drugs that may interact with azithromycin Currently pregnant or lactating women
研究组 & 干预措施
Oral Azithromycin group
The participants in this arm of study will receive only Oral Azithromycin to treat their Acne
干预措施: Azithromycin 250 MG Oral Capsule (Drug)
Oral Azithromycin and Oral probiotic combination
The participants in this arm of study will receive both Oral Azithromycin and Oral Probiotics to treat their Acne
干预措施: Azithromycin 250 MG Oral Capsule Along with Oral Probiotics (Drug)
结局指标
主要结局
Reduction of Acne Lesion Count as per Acne Global assessment scale
时间窗: 12 Weeks
The patients will be assessed before and after the treatment and their lesions will be counted .The Primary outcome that will be measured is the reduction of the lesion counts according to the Acne global Assessment scale The participants included will be with mild to moderate acne on basis of global acne assessment scale score of 2 or 3. The minimum Lesion count considered will be 20 and the Maximum will be 50. Lower is better Higher is worse.
次要结局
未报告次要终点
研究者
Naheed asghar
Associate Professor Dermatology unit HMC
Hayatabad Medical Complex