The Effects of Sleep Variability on Sleep Quality, Daytime Functioning and Cardiometabolic Regulation in Youth
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
- 试验地点
- 1
- 主要终点
- Subjective sleepiness
研究概览
简要总结
Daily sleep variability is prevalent in the young populations, yet its effects remain less clear. The experimental study aims to examine the impacts of intraindividual daily sleep variability on sleep characteristics, cardiometabolic regulations and daytime functioning in college students.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Habitual sleep duration > 7 h/day.
排除标准
- •Extreme morning- nor extreme evening-chronotype
- •With sleep problems
- •With mood and anxiety problems
- •With excessive daytime sleepiness
- •Have history of any chronic medical condition and on regular medication.
研究组 & 干预措施
Irregular sleep
Participants sleep in lab while being monitored with polysomnography for 8 consecutive nights, including an adaptation night and a baseline night of 7.5 h time in bed (0:00-7:30). Afterwards, they are instructed to sleep in bed on a schedule alternated between 6 h, i.e. 1:30-7:30, and 9 h, i.e. 22:30-7:30).
干预措施: Irregular sleep (Behavioral)
Regular sleep
Participants sleep in lab while being monitored with polysomnography for 8 consecutive nights of 7.5 h time in bed (0:00-7:30).
结局指标
主要结局
Subjective sleepiness
时间窗: 7 days (every morning and evening)
As measured by the Stanford Sleepiness Scalen (SSS)
Cognitive functioning - processing speed
时间窗: 7 days
Processing speed as measured by Digit Symbol Substitution Test (DSST)
Cognitive functioning - Sustained attention
时间窗: 7 days (every morning and evening)
Sustained attention as measured by psychomotor vigilance task (PVT)
Cognitive functioning - inhibition
时间窗: 7 days
Inhibition as measured by stop-signal reaction time (SSRT)
Mood
时间窗: 7 days (every morning and evening)
mood state as measured by the Positive and Negative Affect Scale (PANAS).
Cognitive functioning - working memory
时间窗: 7 days
working memory as measured by 2-back task
次要结局
- Cortisol awakening response(baseline, post-intervention)
- Sleep quality(7 days)
- Heart rate variability(7 days)
- Sleep architecture(7 days)
研究者
Dr. Shirley Xin Li
Director of the Sleep Research Clinic and Laboratory
The University of Hong Kong