Role of Fluoxetine in Obsessive Compulsive Symptoms in Schizophrenia
- Conditions
- Health Condition 1: F20- Schizophrenia
- Registration Number
- CTRI/2023/01/048718
- Lead Sponsor
- Government Medical College and Hospital Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1 Patients with diagnosis of Schizophrenia as per ICD 11 and presence of Obsessive Compulsive Symptoms as per Yale Brown Obsessive Compulsive Symptom Checklist
2 Patients having capacity as per Section 4 of Mental Health Care Act 2017 to give written consent or Nominated Representative agreeing to give written consent when the patient does not have adequate capacity
3 Patients on stable dose of antipsychotic medications for the past 3 months (no more than 50% reduction or increase in antipsychotic medications)
4 Age 18 to 65 years
5 Any gender
1 Patients with active substance use disorder within the past 6 months (fulfilling the ICD 11 criteria for substance dependance) except caffeine and nicotine
2 Patients with any acute medical or surgical illness or receiving concomitant medications with contraindications to Fluoxetine
3 Pregnant and Lactating patients
4 Actively suicidal patients or those having high suicidal risk currently
5 Patients already on SSRI and/or Clomipramine for any other co morbid psychiatric condition
6 Patients receiving non pharmacological intervention like ERP or CBT
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the response to treatment with Fluoxetine in persons with Schizophrenia having Obsessive Compulsive SymptomsTimepoint: Assessment shall be done at baseline, 2 weeks, 4 weeks, 6 weeks and 8 weeks
- Secondary Outcome Measures
Name Time Method 1 To study the association among various socio-demographic and clinical correlates in persons with Schizophrenia having OCS and OCD <br/ ><br>2 Compare pre and post treatment changes in OCS and other symptom profile in SchizophreniaTimepoint: Baseline, 8 weeks