Volume-Controlled vs Pressure-Regulated Volume Control Ventilation in Pediatric Anesthesia: an Electrical Impedance Tomography Based Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 123
- 试验地点
- 1
- 主要终点
- Intra-lung Compliance
研究概览
简要总结
The primary goal of this prospective, observational crossover study is to investigate mechanical and EIT (Electrical Impedance Tomography) differences between Volume-Controlled Ventilation (VCV) and Pressure-Regulated Volume Controlled Ventilation (PRVC) in pediatric patients undergoing general anesthesia with endotracheal intubation.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists' status 1 and 2
- •Provision of general anesthesia requiring endotracheal intubation
排除标准
- •chronic lung diseases
- •thoracic surgery
- •thoracic or airway malformation
- •presence of tracheostomy
- •acute pulmonary conditions (secretions, laryngospasm, bronchoconstriction, pneumothorax) during anesthesia
结局指标
主要结局
Intra-lung Compliance
时间窗: Perioperatory.
Intra-lung Compliance is an EIT- based parameter which shows if, between the two modes of ventilation, there is a net gain or loss of intraprenchimal compliance. This is expressed as percentage change from the first-point Compliance measured. We will compare Compliance in PRVC to RVD in VCV ventilation. VCV is the reference point.
次要结局
- Regional Ventilation Delay (RVD)(Perioperatory.)
- Global Inhmogeneity Index (GI)(Perioperatory.)
研究者
Anna Camporesi
Medical Coordinator for Pediatric Anesthesia
Vittore Buzzi Children's Hospital