CTRI/2022/01/039146招募中未知
Comparative Efficacy of Various Non-invasive Methods in Assessing Response to Beta-blockers as Secondary Prophylaxis for Acute Variceal Bleed
试验速览
- 阶段
- 未知
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •1) Clinical / radiological /histologic diagnosis of cirrhosis (Child A&B)
- •2) Age >18 years
- •3) Advanced compensated liver disease of different etiology(Viral,metabolic,alcoholic)
- •Upper GI bleed
- •4) Valid consent
- •5) No history of NSBB use in last 6 weeks
排除标准
- •1) Age > 70 years
- •2) Portal vein thrombosis
- •3) Underlaying shunts
- •4) Spleen anteroposterior diameter <4cm
- •5) Non cirrhotic portal hypertension
- •6) Only PHG, Ectopic varices
- •7) Heart rate <50bpm, SBP <100mm of Hg,Asthma, COPD, Aortic disease, atrioventricular block, Peripheral vascular disease.
- •8) Pregnancy
- •9) obese(BMI >30mm of Hg)
- •11) HCC / Other malignancy
- •12) Other Comorbidities: Chronic kidney disease [ CrCl < 30] 13) Cirrhosis : Child C Stroke Cardiac failure, Uncontrolled diabetes(HbA1c >9)
- •13) AST/ALT >5 times
- •14) Drug allergies
- •16) Narrow intercoastal space
- •17) Failure to give informed consent from family members.
- •18) Patient enrolled in other clinical study
研究者
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