Effect of cardiac physiotherapy on the quality of life and frailty profile of women with breast cancer undergoing chemotherapy
- Conditions
- Breast Neoplasms
- Registration Number
- RBR-4j2g5qj
- Lead Sponsor
- niversidade do Planalto Catarinense
- Brief Summary
Introduction: Breast cancer is the most common neoplasm in the Brazilian female population. It is already known that the progressive increase in cancer survival rates also goes hand in hand with the increase in mortality of these individuals from other causes, such as cardiovascular diseases. These are commonly developed as a result of cardiotoxic oncological treatments. Physical exercise contained in cardiac rehabilitation programs has been shown to be effective in preventing and treating these adverse effects. However, the literature lacks further investigation of the effect of physical exercise on the quality of life, physical function and quality of sleep of breast cancer patients undergoing chemotherapy. Objective: To evaluate the effect of cardiac rehabilitation on the quality of life, physical function and quality of sleep of breast cancer patients undergoing chemotherapy. Methods: Experimental study, which intentionally allocated nine women diagnosed with breast cancer undergoing chemotherapy treatment 1:1, divided into two groups: intervention group (five participants) and control group (four participants). The intervention group participated in an aerobic and resistance exercise program, three times a week, for three months, while the control group received a booklet with recommendations on physical exercise. The sociodemographic, clinical and lifestyle profile were evaluated, as well as functional capacity, cardiorespiratory capacity, peripheral and respiratory muscle strength, body composition, quality of life and quality of sleep before and after the intervention in both groups. Results: The sample was composed of white women, with a mean age of 52 (±10) years, non-drinkers and non-exercisers, with the majority having invasive ductal carcinoma as histological type of breast cancer (55.6 %). A significant improvement in general quality of life was observed only in the intervention group, as well as an improvement in functional capacity due to gait speed. No significant differences were obtained in body composition, peripheral and respiratory muscle strength and sleep quality in both groups. Conclusion: Cardiac rehabilitation, in addition to being safe, proved to be effective in improving the quality of life and functional capacity of women with breast cancer undergoing chemotherapy, and can be used as a beneficial tool for intervention
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Terminated
- Sex
- Female
- Target Recruitment
- Not specified
Women over 18 years old diagnosed with breast cancer, ductal carcinoma in situ or stages I to III, undergoing chemotherapy treatment. Agree to participate in the study by signing the free and informed consent form
Patients with self-reported physical or mental inability (assessed by the Mini-mental State) to perform the proposed exercises. Unavailability to participate in all stages of the research. Do not attend 75% of the proposed exercise program. Have had unstable angina or acute myocardial infarction in the last 30 days
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cardiac rehabilitation is expected to improve the quality of life and the frailty profile of patients with breast cancer undergoing chemotherapy, verified by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire BR23 and Fried frailty test
- Secondary Outcome Measures
Name Time Method Cardiac rehabilitation is expected to reduce oxidative stress, improve the metabolic profile, body composition and cardiorespiratory capacity in the intervention group