NCT00886860已完成4 期
The Comparison of Efficacy for Cervical Ripening in Labor Induction Between Titrated and Conventional Oral Misoprostol
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- success rate of cervical ripening in labor induction
研究概览
简要总结
The purpose of this study is to compare the efficacy for cervical ripening in labor induction between titrated and conventional oral misoprostol
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •age 18 years old or more
- •singleton pregnancy at 37 weeks gestation or more
- •cephalic presentation
- •reassuring fetal heart rate pattern
- •admission for labor induction due to medical or obstetrical conditions
- •bishop score less than 6
- •giving consent and having signed the consent form for this study
排除标准
- •parity more than 3
- •estimated fetal weight more than 3,500 grams
- •non-reassuring fetal heart rate pattern
- •having contraindication for vaginal delivery
- •previous uterine scar
- •suspected abruptio placenta with non-reassuring fetal heart rate pattern
- •abnormal bleeding per vagina, except bloody show
- •having underlying cardiac, hepatic, or renal diseases
- •having history of allergy to misoprostol or prostaglandin analogues
- •cervical dilatation 3 centimeters or more
- •uterine contraction 3 times or more in 10 minute
研究组 & 干预措施
conventional oral misoprostol
Active Comparator
misoprostol 50 micrograms oral every 4 hours until cervical dilatation 3 centimeters
干预措施: misoprostol (Drug)
titrated oral misoprostol
Experimental
misoprostol 20 micrograms oral every hour until cervical dilatation 3 centimeters
干预措施: misoprostol (Drug)
结局指标
主要结局
success rate of cervical ripening in labor induction
时间窗: 12 hours after intervention
次要结局
- number of vaginal delivery(24 hours)
研究者
研究点 (1)
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