Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

Not Applicable

Completed

• Conditions: Psoriasis Vulgaris

• Registration Number: NCT00236171
• Lead Sponsor: Technische Universität Dresden

Brief Summary

The purpose of this study is to evaluate the efficacy of the topical therapies Protopic and Advantan as well as their combination against placebo in a Psoriasis Plaque Test

Detailed Description

daily psoriasis plaque tests for two weeks and optical coherence tomography (OCT) and 20-MHz-ultrasound on day 0 and day 11, 10 days post end of treatment and 20 days post end of treatment

Study Timeline

• Study Start: 2004-09
• Study First Submitted: 2005-10-04
• Study First Submitted QC: 2005-10-10
• Study First Posted: 2005-10-12
• Primary Completion: 2006-04
• Status Verified: 2010-06
• Study Completion: 2010-06
• Last Update Submitted: 2010-06-07
• Last Update Posted: 2010-06-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Patients older than 18 Years
• Negative urine pregnancy test
• Written informed consent
• Good compliance

Exclusion Criteria

• Patients less than 18 years
• Pregnant patients
• Patients with renal insufficiency, liver diseases
• Patients who received systemic antipsoriatic treatment or UV treatment less than 4 weeks prior to study
• Patients who used topical antipsoriatics within two weeks prior to study
• Immunosuppressed Patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
sum score of psoriasis plaque tests on day 11

Secondary Outcome Measures

Name	Time	Method
20-MHz-ultrasound and OCT on day 11

Trial Locations

Locations (1)

Technische Universität Dresden; 🇩🇪 Dresden, Sachsen, Germany