Single-centre, Registry Trial, the Patients Presented With Stable Coronary Artery Disease

Completed

Brief Summary: This is a prospective study to analyze the outcome of provisional main vessel stenting on side branch by utilizing Two-Dimensional (2D) and Three-Dimensional (3D) frequency domain optical coherence tomography (FD-OCT). To analyze the fate of side-branch after provisional main vessel stenting based on morphology defined prior to PCI by OCT. Offline analysis of side branch impingement of the ostium of SB leading to acute loss in SB diameter area, carina shift and plaque shift will be also be performed.

Detailed Description: Patients with stable coronary artery disease with angiographic main vessel lesion not involving side branch (SB) in whom provisional stenting strategy is planned will be recruited. All the participants of the registry will receive same stent. OCT will be performed to analyze plaque morphology, SB size, SB angle and side branch ostial involvement.

Recruitment & Eligibility

Inclusion Criteria

Over 18 years of age presenting with stable coronary artery disease.
Angiographic lesion not involving side branch (SB) in whom provisional main vessel stenting strategy is planned after reviewing angiogram will be recruited

Exclusion Criteria

Patient with lesion involving side branch ( >70 %) by angiogram and need pre-dilation.
Patients with ostial left main artery lesions or ostial right coronary artery lesions
Female patients with child bearing potential not taking adequate contraceptives or currently breastfeeding
Known allergy to acetylsalicylic acid or clopidogrel.
Planned surgery within 12 months.
History of bleeding diathesis
Major surgery within 15 days
Life expectancy < 12 months.
Patients with kidney dysfunction (CrCl<30)

Primary Outcome Measures

Name	Time	Method
MLD SB Diameter	day 1	Optical coherence tomography (OCT) - a high resolution intravascular imaging technique to assess side branch size. Side branch diameter will be measured by QAngio OCT software from Medis. Three-Dimensional Quantitative Coronary Angiography (3D-QCA) Analysis of Bifurcation Lesions Before (PRE) and After (POST) Provisional Stenting. Main vessel minimal lumen diameter (MLD)

Secondary Outcome Measures

Name	Time	Method
SB Angle	day 1	Optical coherence tomography - a high resolution intravascular imaging technique to assess side branch (SB) angle. Side branch angle will be measured by QAngio XA 3D software (Medis). Three-Dimensional Quantitative Coronary Angiography (3D-QCA) Analysis of Bifurcation Lesions Before (PRE) and After (POST) Provisional Stenting. Bifurcation angles (BA)
SB Ostial Involvement	day 1	Optical coherence tomography - a high resolution intravascular imaging technique to assess side branch ostial involvement. Side branch area will be measured by QAngio OCT software (Medis). Three-Dimensional Quantitative Coronary Angiography (3D-QCA) Analysis of Bifurcation Lesions Before (PRE) and After (POST) Provisional Stenting. Minimal lumen diameter (MLD)
Diameter Stenosis (DS)	day 1	Three-Dimensional Quantitative Coronary Angiography (3D-QCA) Analysis of Bifurcation Lesions Before (PRE) and After (POST) Provisional Stenting. Side Branch Ostium Diameter Stenosis (DS).