Prednisolone: Could it be a new treatment option for cystic fibrosis lung flare-ups?
- Conditions
- Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
- Registration Number
- CTRI/2023/10/058586
- Lead Sponsor
- Post Graduate Institute of Medical Education and Research Chandigardh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1)Confirmed diagnosis of cystic fibrosis based on:
Newborn screening or at least one clinical feature of CF, AND either (a) or (b) as follows:
a) Documented sweat chloride = 60 mEq/L by quantitative pilocarpine iontophoresis
b)Genotype with two identifiable CF-causing mutations.
2)Age > 6 years old.
3)Acute pulmonary exacerbation as per Fuchs criteria
1)Active allergic bronchopulmonary aspergillosis (ABPA) at the time of enrollment as determined by the treating physician.
2)Uncontrolled hypertension with suspected end organ damage
3)Physical findings that could potentially compromise the safety of the participant or the quality of the study data as determined by site investigator.
4)Children enrolled in the study within the preceding twelve months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method