NCT00002066已完成不适用
Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection
Immunobiology Research Institute2 个研究点 分布在 1 个国家开始时间: 2001年8月31日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 2
研究概览
简要总结
Examine the ability of thymopentin (Timunox) to:
Reduce the amount and/or frequency of virus isolation. Stimulate the immune system and alter the clinical findings in patients infected with HIV who do not yet have AIDS.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Concurrent Medication:
- •Aerosolized pentamidine.
- •Prior Medication:
- •Aerosolized pentamidine.
排除标准
- •Co-existing Condition:
- •Patients with an abnormal chest x-ray indicative of active disease (opportunistic infection) within 30 days prior to entry are excluded.
- •Concurrent Medication:
- •Excluded within 90 days of study entry:
- •Zidovudine (AZT).
- •Prior Medication:
- •Excluded within 30 days of study entry:
- •Immunomodulatory or experimental therapy.
- •Excluded within 90 days of study entry:
- •Zidovudine (AZT).
- •Patients must not have:
- •Hemophilia A or B or other hematologic disorders requiring current or previous administration of blood products.
- •AIDS as defined by the CDC (except for those with HIV "wasting syndrome").
- •Significant hepatic disease.
- •Thrombocytopenia (< 75000 platelets/mm3).
- •Patient must voluntarily sign consent and be seropositive for HIV-1 (ELISA assay) confirmed by Western blot.
- •HIV-1 p24 antigen must be detected in supernatant fluids from co-cultures of patient's peripheral blood monocytes (PBMC) on two separate occasions.
- •Patients with HIV "wasting syndrome" are included.
- •Intravenous drug abuse.
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Double Blind Study of Thymopentin Effects on Patients With HIV-1 InfectionHIV InfectionsNCT00002051Immunobiology Research Institute
已完成
不适用
Double Blind Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected PatientsHIV InfectionsNCT00002049Immunobiology Research Institute
已完成
不适用
The Effects of Thymopentin on HIV Infectivity of Blood Cells and Semen in HIV-Infected PatientsHIV InfectionsNCT00002289Immunobiology Research Institute
已完成
2 期
A Study of Timunox (Thymopentin) in HIV-Infected Patients Receiving Other Anti-HIV DrugsHIV InfectionsNCT00002332Immunobiology Research Institute60
已完成
不适用
A Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected PatientsHIV InfectionsNCT00002050Immunobiology Research Institute