Comparison of Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy, A Prospective Randomized Controlled Study
试验速览
- 阶段
- 2 期
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Cumulative morphine use
研究概览
简要总结
The goal of this randomized controlled trial is to compare laparoscopic guided peri-wound Transversus Abdominis Plane Block and bupivacaine versus local wound infiltration effect on reducing post-op opioid use in Laparoscopic Sleeve gastrectomy. The main questions it aims to answer are:
• Can laparoscopic guided peri-wound Transversus Abdominis Plane Block reduced post operative morphine usage when comparing with local wound port site infiltration.
Participants will be randomize into 2 group
- peri-wound Transversus Abdominis Plane Block
- local wound port site infiltration
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient undergoing LSG at Sringarind hospital as indicated by Thai guideline
排除标准
- •Allergic/contraindicated to bupivacaine, morphine, fentanyl, NSAIDs or Nefopam
- •Unable to describe pain score Opioid addict
- •denied consent
研究组 & 干预措施
local wound infiltration
0.25% Bupivacaine 20ml was injected into the wound subcutaneous tissue after the laparoscopic port was removed
干预措施: Local wound infiltration (Procedure)
peri-wound Transversus Abdominis Plane Block
0.25% Bupivacaine 20ml was injected into the transversus abdominis plane around the wound before the laparoscopic port was removed
干预措施: peri-wound Transversus Abdominis Plane Block (Procedure)
结局指标
主要结局
Cumulative morphine use
时间窗: 48hours after intervention
次要结局
- opioid side effect(within admission)
- length of hospital stay(within admission)
- PACU time(1day after intervention)
- postop complication(2weeks after intervention)
- Post op VAS pain score(48hours after intervention)
研究者
Thanatat panitphong
Primary investigator
Khon Kaen University