Ceftaroline (Zinforo®) as antibiotic prophylaxis for CABG-surgery: An In-vivo microdialysis study

MedUni Vienna, Dept of Anesthesia, Critical Care, Div. of Cardiothoracic and Vascular Anesthesia0 个研究点目标入组 18 人开始时间: 2017年12月4日最近更新: 2018年3月26日

适应症

试验速览

暂无简介。

•-Written informed consent
•-Planned coronary artery bypass grafting with left internal mammary artery bypass
•-Planned use of cardiopulmonary bypass
•-Age: > 18 and < 90 years
•-Ejection fraction > 40%
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•-Inability to give informed consent
•-Know allergy to cephalosporins or penicillin or ceftaroline
•-Preoperative antibiotic therapy
•-Signs of infection preoperatively
•-Re-operation or emergency procedure
•-Planned use of bilateral internal mammary artery bypass
•-Preoperative renal failure
•-Chronic severe renal insufficiency including hemodialysis
•-Chronic severe liver disease
•-BMI > 35
•-Long standing diabetes mellitus (> 7 years) and insulin-dependent diabetes mellitus
•-Pregnant women

发起方

MedUni Vienna, Dept of Anesthesia, Critical Care, Div. of Cardiothoracic and Vascular Anesthesia