跳至主要内容
临床试验/CTRI/2025/03/082359
CTRI/2025/03/082359尚未招募不适用

A Randomized Controlled Clinical Study to Evaluate the Efficacy of Vrana Ropak Tail in Management of Dushta Vrana W.S.R. to Infected Wound

Dr VJD Gramin Ayurved Mahavidyalaya1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年4月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
1.Pariman of Vrana (size of wound)

研究概览

简要总结

Vrana and its management has been dotted since period of Veda to Current era. It has been a major problem Since early stage of medical science non-healing wound present serious problem for patient family, and clinician. Most of wound associated with a small number of under lying disorders such as DM, Leprosy and peripheral disease. Wound are Common place from childhood to old age and some time it required surgical intervention.

Dusta means getting vitiated by doshas which one such long standing ulcer with profuse discharge and slough. Vrana healing are two Side of Surgical coin on which surgeon plays important role.

Wound management assisted by cleansing and removal of dead tissue from wound & application of local dressing on wound to create a moist environment. Various factors responsible for improper healing of vrana are vascular insufficiency, contamination of wound disease like D.M, T.B.; Anemia and Malignancy.

Sushruta an eminent surgeon of his era was much ahead of his time in expanding and practicing and beautiful concept of vrana ropana. The aim of wound healing according to Aacharya Sushrut are many of herbs of Herbo-mineral combination for a Vrana Shodhana and ropana activity, for proper healing of wound it is essential to decrease microbial burden, removing on unhealthy slough, necrotized tissue and maintains moisture presence.

Sushruta has formulated 60 procedures i.e. Shashti Upkrama for management of vrana management of vrana along with numerous drugs. Charka has mentioned the 36 procedures of Vrana upkrama.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.All infected wound 2.Chronic non healing wound 3.Wound size up to 5cm by 5cm 4.Patients will be selected irrespective of their gender, caste and socioeconomic status 5.Patient age 20 to 60 yrs will be included 6.Patients ready to give written consent will be selected 7.Wound depth upto Masadhatu.

排除标准

  • 1.Wound created by T.B 2.Burn wounds 3.Leprosy wounds 4.Wound having excessive loss of tissue 5.Patient having malignant ulcers 6.Osteomyelitis 7.Size of wound more than 5cm 8.Patient suffering from HIV, HbsAg, DM 9.Bleeding disorder 10.Patient on aspirin and other antiplatelet drugs 11.Gangrenous 12.Less than 20 yrs and more than 60 yrs of age 13.Wound depth beyond the Masadhatu 14.Medicolegal cases.

结局指标

主要结局

1.Pariman of Vrana (size of wound)

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

2.Strava of Vrana (discharge)

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

3. Strava Ghatak of vrana (discharge content)

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

4.Gandha of vrana (smell)

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

5.Vedana of vrana (pain)

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

6.Varna of vrana (colour)

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

7.Duration of healing

时间窗: Assesment before and after Treatment and follow up at 3,5,7,10,15,21 and 28th day

次要结局

  • Decrease in symptoms of Dustavrana(18 months)

研究者

发起方
Dr VJD Gramin Ayurved Mahavidyalaya
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Rameshwar Bhujang Khedkar

Dr VJD Gramin Ayurved Mahavidyalaya

研究点 (1)

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