Determination of exercised-induced bronchoconstriction with a standardized exercise test for infants and young children (3-6 years).

Withdrawn

• Conditions: childhood asthma; wheezing disorder in infants; 10006436

• Registration Number: NL-OMON31591
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Age: 3-6 years
-Asthma:
Children with episodic attacks (>3 times/year) of wheeze, shortness of breath or cough.
-Controls:
Healthy, no respiratory smptoms

Exclusion Criteria

-recent respiratory infection,
-severe respiratory symptoms with need for oral steroids,
-history of prematurity and/or intensive care treatment,
-other respiratory disorders such as Cystic Fibrosis,
-other disorders that limit the possibily to perform an exercise test

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>-Number of children with exercise-induced bronchoconstriction in the wheeze<br /><br>group compared to the healthy group.<br /><br>-Number of children with bronchoconstriction measured by FOT at 3-6 years of<br /><br>age compared to number of children with bronchoconstriction measured with<br /><br>treadmill/ histamine challenge at 7-8 years of age.<br /><br>-Number of children able to perform the test at 3-6 years<br /><br>-Reproducibility</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>