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临床试验/NCT02878941
NCT02878941已完成不适用

Synovial Fluid Analysis of Intraarticular Elbow Fracture

Duke University2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2017年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
12
试验地点
2
主要终点
metabolite composition of synovial fluid

研究概览

简要总结

The objective of this study is to obtain and compare bilateral elbow joint synovial fluid from patients with unilateral intraarticular elbow fracture and a contralateral healthy appearing elbow joint. The synovial fluid samples will undergo several forms of analysis for metabolites and proteins. Matched-pair statistical analysis will be performed to determine the metabolites and proteins that may play the greatest role in development of joint contracture.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18 years and older
  • Intraarticular elbow fracture (humerus, radial head and/or ulna fracture)

排除标准

  • Age <18 years
  • Open elbow fracture
  • Bilateral elbow fractures
  • Patients with history of osteomyelitis of elbow
  • Inflammatory arthropathy (ie. Rheumatoid arthritis)
  • Prior surgery on fractured elbow

结局指标

主要结局

metabolite composition of synovial fluid

时间窗: time of fracture until surgical fixation (up to 5 weeks after injury)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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