Joint hypermobility: effect of a strength training program on disability and functio

Not Applicable

Completed

• Conditions: Joint Hypermobility; Musculoskeletal Diseases; Hypermobility syndrome

• Registration Number: ISRCTN90224545
• Lead Sponsor: Bern University Hospital (Switzerland)

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33557909/ results (added 10/02/2021) Abstract results in https://www.researchgate.net/publication/319529276_Effect_of_Resistance_Training_in_Women_with_Joint_Hypermobility_-_Results_of_a_Pragmatic_Randomised_Controlled_Trial results presented at the World Congress of Physiotherapy (added 13/08/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-07-16
• Study Completion: 2016-12-14
• Last Update Posted: 24 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 51

Inclusion Criteria

1. Women with generalized joint hypermobility
2. 20 to 40 years old
3. Normal body mass index (BMI) (between 18-30 kg/m2)
4. At least 6/9 points in the Beighton score
5. Right knee extension beyond 10°
6. Able to understand German questionnaires

Exclusion Criteria

1. Surgery of the legs or lumbar spine in the last two years
2. Doing more than four hours per week of regular intense sports
3. Pregnancy or less than one year after delivery
4. Known genetic diseases of connective tissue like Marfan syndrome and Osteogenesis imperfecta, as well as Ehler-Dahnlos-syndrome I and II

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effect of strength training is the increase in muscle strength, measured as maximum isometric strength and the rate of force development (RFD) of knee extensors and knee flexors on a custom-built strength measurement table with a force transducer. Measured at baseline, after training respectively waiting period (12 weeks) and three months after end of the training.