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Clinical Trials/NCT05088265
NCT05088265
Enrolling By Invitation
Not Applicable

Prospective Real World Data Collection for the Bigfoot Unity Diabetes Management System

Bigfoot Biomedical Inc.1 site in 1 country500 target enrollmentOctober 26, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 1 or Type 2 Diabetes
Sponsor
Bigfoot Biomedical Inc.
Enrollment
500
Locations
1
Primary Endpoint
Percent time Sensor in range of 70 mg/dL to 180 mg/dL, inclusive
Status
Enrolling By Invitation
Last Updated
3 years ago

Overview

Brief Summary

This study is observational, designed to collect real world use and safety data for those using the Bigfoot Unity Diabetes Management System for 12 months. Participants will be those with a prescription to use the Bigfoot Unity System. Medical practices prescribing Bigfoot Unity and Sponsor representatives will provide information about the study to current users and individuals considering initiation of the Bigfoot Unity System. During the course of the study, participants will be asked to use the Bigfoot Unity System in accordance with the prescription provided by their healthcare professional (HCP).

Registry
clinicaltrials.gov
Start Date
October 26, 2021
End Date
February 2025
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Type 1 or type 2 diabetes diagnosis
  • HCP-prescribed, registered Bigfoot Unity users who have used the Bigfoot Unity System 2 weeks or less
  • Age 12 years or older at time of electronic informed consent
  • Using both long-acting and rapid-acting insulins that are compatible for use with the Bigfoot Unity System
  • Using long-acting insulin no more than 1 time per day
  • Must have baseline HbA1c collected within 90 days prior to starting the Bigfoot Unity System
  • Able to read and understand English
  • Participant or legally authorized representative for minors has the capacity to provide electronic informed consent
  • Resident of the United States
  • Persons who are using a phone that is compatible with Bigfoot Unity and not shared with a family member or a caregiver

Exclusion Criteria

  • Females who are pregnant or intending to become pregnant during participation in the study
  • Persons with implantable medical devices such as pacemakers
  • Persons on dialysis or other serious medical conditions that would impact the ability to use the device or manage their diabetes
  • Persons taking or expected to be taking \>500mg Vitamin C supplements on routine basis
  • Persons employed by the Sponsor or JCHR

Outcomes

Primary Outcomes

Percent time Sensor in range of 70 mg/dL to 180 mg/dL, inclusive

Time Frame: 12 months

Glucose management indicator

Time Frame: 12 months

Change from baseline in HbA1c

Time Frame: 12 months

Glycated hemoglobin

Change from baseline in Insulin Delivery Satisfaction Survey

Time Frame: 12 months

Measures the effectiveness, burdensomeness and inconvenience of an insulin delivery system; scale is 1.0 to 5.0, higher scores are better.

System Usability Scale

Time Frame: 12 months

Measures the usability of a system; scale is 0 to 100, higher scores are better.

Percent time Sensor in hypoglycemia

Time Frame: 12 months

Will evaluate Sensor below 70 mg/dL and below 54 mg/dL

Percent time Sensor in hyperglycemia

Time Frame: 12 months

Will evaluate Sensor above 180 mg/dL and above 250 mg/dL

Change from baseline in Diabetes Distress Scale

Time Frame: 12 months

Measures emotional and behavioral challenges generated by diabetes and its management; scale is 1.0 to 6.0, higher scores are worse.

Change from baseline in Hypoglycemia Confidence Scale

Time Frame: 12 months

Measures the degree to which people with diabetes feel able, secure, and comfortable regarding their ability to stay safe from hypoglycemic-related problems; scale is 1.0 to 4.0, higher scores are worse.

Study Sites (1)

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