Prevalence of SARS-CoV-2 in Conjunctival Swab Samples Among Patients Presenting With Conjunctivitis to the Ophthalmology Clinics During the COVID-19 Pandemic
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Proportion of conjunctival samples tested positive for SARS-CoV-2
研究概览
简要总结
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly identified, highly contagious RNA virus causing respiratory infectious disease, Coronavirus Disease 2019 (COVID-19). Conjunctivitis has been reported as a rare finding of the disease, and preliminary studies showed that the virus RNA could be detected in ocular secretions using polymerase chain reaction (PCR) assays when conjunctivitis present. This study aims to estimate the proportion of SARS-CoV-2 associated conjunctivitis among patients with suspected viral conjunctivitis presented to the ophthalmology clinics of Wilmer Eye Institute during the COVID-19 pandemic. The investigators also aim to identify whether SARS-CoV-2 associated conjunctivitis is an isolated finding or an early sign of COVID-19.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 years old or older
- •Willingness to participate
- •Presents with red eye complaint
排除标准
- •Adults lacking capacity to consent
- •Adults with special needs due to physical, medical, developmental or cognitive conditions
结局指标
主要结局
Proportion of conjunctival samples tested positive for SARS-CoV-2
时间窗: 1 year
Number of conjunctival samples with positive PCR divided by the total number of conjunctival samples
次要结局
- Positive conjunctival sample rate in patient developed COVID-19(1 year)
- Proportion of nasal samples tested positive for SARS-CoV-2 among patients with positive conjunctival samples(1 year)
- Proportion of nasopharyngeal samples tested positive for SARS-CoV-2 among patients with positive conjunctival samples(1 year)
- Rate of development of COVID-19 in the study patient population(1 year)