Anti KU Antibodies and Its Relationship With Systemic Lupus Erythematosus
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Anti KU antibodies and its relationship with Systemic Lupus Erythematosus manifestations
研究概览
简要总结
systemic lupus Erythematosus (SLE) is a multi system autoimmune disorder abroad spectrum of clinical presentations.
Diagnosis of SLE depending on Systemic Lupus International Collaborating Clinics (SLICC) Criteria.
SLICC Criteria requires either that a patient satisfy at least 4 of 17 Criteria including at least 1 of 11 clinical criteria and 1 of 6 immunological criteria or the patient has biopsy -proven nephritis compatible with SLE in the presence of antinuclear antibodies (ANA)or anti_double stranded DNA (dsDNA) antibodies.
Anti_KU antibodies included in (ANA), reported in many autoimmune disorders like SLE,Sjogren syndrome, idiopathic lung fibrosis and myositis.
So the aim of the work is to determine the relationship between Anti_KU antibodies and SLE manifestations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 17 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients will fulfill the Systemic Lupus International Clinics(SLICC) classification criteria for Systemic Lupus Erythematosus.
排除标准
- •any patient with any collagen disease other than SLE
结局指标
主要结局
Anti KU antibodies and its relationship with Systemic Lupus Erythematosus manifestations
时间窗: 6 months
the study will evaluate the titre of Anti KU antibodies which is positive or negative in one patient and on the other side what is the manifestation of SLE that found in the same patient if the Anti KU Antibodies titre is positive
次要结局
未报告次要终点
研究者
Nehal Abdelbasset Ahmed
Resident Doctor at Rheumatology Department
Sohag University