Examination of ocular blood flow and reduction of intraocular pressure, comparing Tafuluprost and Tafuruprost Bunazosin with primary open angle Glaucoma.

Not Applicable

• Conditions: Glaucoma

• Registration Number: JPRN-UMIN000011319
• Lead Sponsor: Department of Ophthalmology, Kanazawa University

Brief Summary

Instillation of tafluprost significantly reduced intraocular pressure, but there was no change in microcirculation of optic disc.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2009-11-04
• Study Start: 2013-07-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients who have ocular diseases without glaucoma and mild cataract(diabates retinopathy or morbid myopia or etc) 2) Progressive or severe glaucoma(for example using a Humphery field analyzer,MD <-12dB,0dB detection is in 5degree) 3) Patients with any corneal abnormality or other condition preventing reliable applanation tonometry. 4) Patients with anamnestic hitory of hypersensitivity to prostagrandin analogs and benzalkonium chloride. 5) Patients with active external ocular diseases,ocular inflammation or infection. 6) Patients with history of reflactive surgery. 7) Patients with history of internal ocular surgery within 6month before the study (cataract surgery,SLT,trabecrctomy,trabecrotomy etc). 8) Smoker 9) Patients who are unable to undergo ocular blood flow test. 10) Pregnant,lactating women ,the women who desired of the pregnancy during the test period. 11) Patients who are going to use prohibited drugs during test period. 12) Doctor judged to be inelible to the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified