NCT02541188终止不适用
Genotype and Phenotype in Early Onset Breast Cancer in Young Women on the Two Shores of the Mediterranean Sea
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 460
- 试验地点
- 1
- 主要终点
- Genetic analysis of Breast Cancer susceptibility gene 1 (BRCA 1)
研究概览
简要总结
Breast cancer are common on mediterranean basin. Epidemiological data suggest that breast cancer in young women (< 40years old) is more aggressive in the Maghreb countries comparatively to western countries. This aggressiveness could be associated with phenotypic and genotypic differences between this two populations.
详细描述
The object of this study is to compare the genotypic and phenotypic differences between south and north shore of the mediterranean sea.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patient have or have had a breast cancer diagnosed before 40 years old
- •Breast cancer proven by histology
- •BRCA1/2 analysis proposed, realized, ongoing
- •Women >18 years old
- •Patient with insurance
- •Patient informed and no-opposed
排除标准
- •Patient have or have had a breast cancer diagnosed after 40 years old
- •Patient requiring tutorship or guardianship
- •Adult patient protected by law
结局指标
主要结局
Genetic analysis of Breast Cancer susceptibility gene 1 (BRCA 1)
时间窗: The day of inclusion
Genetic analysis of Breast Cancer susceptibility gene 2 (BRCA 2)
时间窗: The day of inclusion
次要结局
- analysis of HER2(The day of inclusion)
- Analysis TNM grade(The day of inclusion)
- growth factors analysis (Ki 67)(The day of inclusion)
- analysis of hormone receptor PR(The day of inclusion)
- Analysis histoprognostic grade Scarf Bloom and Richardson (SBR)(The day of inclusion)
- analysis of hormone receptor ER(The day of inclusion)
研究者
研究点 (1)
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