CTRI/2023/01/048844招募中未知
Integrated multi-omics and machine learning to decipher pathobiology and outcomes in alcoholic hepatitis patients
ICMR0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •1. Patients age 18 to 80 years
- •2. Patients with probable or definite alcoholic hepatitis (AH) (as per AASLD guidelines)
- •will be enrolled from consecutive patients presenting first time to the department.
- •The diagnosis of AH will be made as per the NIAAA consensus, i.e.,
- •onset of jaundice within the prior eight weeks,
- •ongoing consumption of >40g (female) or >60 (male)g of alcohol/day for 6 months or
- •more, with less than 60 days of abstinence before the onset of jaundice
- •aspartate aminotransferase >50, aspartate aminotransferase/alanine aminotransferase
- •>1.5, and both values <400IU/L
- •serum bilirubin (total) >3.0 mg/dL
- •liver biopsy confirmation in patients with confounding factors
排除标准
- •Patients having:
- •i. HIV infection
- •ii. Prior organ transplantation
- •iii. Hepatic or extra-hepatic malignancy
- •iv. Receiving any experimental therapies
- •v. Pregnant or lactating women, will be excluded
研究者
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