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Clinical Trials/NCT03501654
NCT03501654
Unknown
Not Applicable

Prospective Clinical Trial of Unilateral or Bilateral Implantation of the Enlarged Depth-of-focus Intraocular Lens in Cataract Patients With Presbyopia

Seoul National University Hospital1 site in 1 country20 target enrollmentFebruary 17, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cataract
Sponsor
Seoul National University Hospital
Enrollment
20
Locations
1
Primary Endpoint
Change of visual acuity at near, intermediate and far
Last Updated
8 years ago

Overview

Brief Summary

This is to evaluate the satisfaction of patient and physician about short-distance, medium-distance, long-distance postoperative vision and eyeglass dependence, glare, and visual acuity after insertion of the TECNIS® Symfony or TECNIS® Symfony Toric intraocular lens.

Detailed Description

The patients underwent uneventful phacoemulsification and implantation of TecnisSymfony®. Mean absolute error (MAE) at 1 month was compared in SRK/T, Holladay2, Haigis, Hoffer Q, Barrett Universal II, and Hill-RBF formula. At postoperative 1, 4, and 12 weeks, logMAR visual acuity (logMARVA) at the distance (5m), intermediate (66cm), and near (40cm), and spherical equivalent (SE) in manifested refraction (MR) and automated refraction (AR) were measured. Wavefront aberration, contrast sensitivity test, and glare test were done at 12 weeks. The questionnaire was used to investigate glare, glasses dependency, and patient satisfaction at 12 weeks.

Registry
clinicaltrials.gov
Start Date
February 17, 2017
End Date
December 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mee Kum Kim

Professor

Seoul National University Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients with unilateral or bilateral cataract
  • Sixteen years and older
  • Regular corneal topography and corneal astigmatism
  • Corneal astigmatism 0.75 Diopter and less for TECNIS® Symfony IOL, and between 1.0 and 3.62 Diopter for TECNIS® Symfony toric IOL

Exclusion Criteria

  • Pregnant or nursing women
  • In the presence of other ocular diseases that may affect the stability of the lens capsule (pseudoexfoliation syndrome, glaucoma, traumatic cataract, Malfan syndrome, etc.)
  • White cataract
  • Patients who need intraocular lens outside of range
  • In the presence of other ocular diseases that is expected to have a poor final visual acuity of less than 20/30 after surgery (amblyopia, strabismus, keratoconus, etc.)
  • Pupil abnormality (non-reactive pupil, tonic pupils, abnormally shaped pupils, etc.)
  • Patients using systemic or ocular medication that affect visual acuity.
  • Patients who had previously undergone refractive surgery.
  • Patients participating in other clinical trials during the study.

Outcomes

Primary Outcomes

Change of visual acuity at near, intermediate and far

Time Frame: preoperative(last outpatient follow-up before the surgery), 1 month after surgery, 3 months after surgery.

LogMAR visual acuity (logMARVA) at the distance (5m), intermediate (66cm), and near (40cm) were measured at preoperative (last outpatient follow-up before the surgery), postoperative 1, 4, and 12 weeks.

Secondary Outcomes

  • Spectacle dependence evaluation by questionnaire(One month and three months after the surgery.)
  • Photic phenomena evaluation by questionnaire.(One month and three months after the surgery.)

Study Sites (1)

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