NCT00634400已完成3 期
Candesartan in Heart Fail. Assess. of Reduction in Mortality & Morbidity. Candesartan in Patients With Heart Failure Who Are ACE Inhibitor Intolerant and Have Depressed Left Ventricular Systolic Function
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 6,268
- 主要终点
- Cardiovascular mortality or hospitalisation due to congestive heart failure
研究概览
简要总结
A study to evaluate the effect of Atacand on patients with heart failure with depressed left ventricular function
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female aged 18 or above
- •Congestive Heart Failure with symptoms for more than 4 weeks before starting study
- •Provision of informed consent
排除标准
- •Current low blood pressure with symptoms
- •Liver disease considered significant by the study doctor
- •Pregnant or lactating females
研究组 & 干预措施
1
Active Comparator
干预措施: Candesartan (Drug)
2
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
Cardiovascular mortality or hospitalisation due to congestive heart failure
时间窗: 2, 4, 6 weeks, 6 months, every 4 months thereafter until 24 months
次要结局
- Cardiovascular mortality or hospitalisation for management of congestive heart failure, or non fatal MI(2, 4, 6 weeks, 6 months, every 4 months thereafter until 24 months)
研究者
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