Does removal of cerebrospinal fluid from lowerback in surgery for the pituitary tumor decrease the cerebrospinal fluid leak through the nose
Phase 3
- Conditions
- Health Condition 1: null- Pituitary adenoma
- Registration Number
- CTRI/2014/09/005021
- Lead Sponsor
- CMC Vellore IRB
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
All patients newly diagnosed to have a pituitary adenoma and undergoing endoscopic transsphenoidal surgery
Exclusion Criteria
Patients in whom an expanded endoscopic transsphenoidal surgery is planed will be excluded since we intentionally open the arachnoid over the planum sphenoidale in these cases
Previous transsphenoidal surgery , Previous radiation therapy , patients with spinal deformities and patients with deranged bleeding parameters
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the incidence of intraoperative and postoperative CSF leakTimepoint: Intraoperative leak will determined by the surgeon at the time of surgery. The postoperative leak will be determined by the ENT surgeon on the seventh postoperative day through a nasal scopy
- Secondary Outcome Measures
Name Time Method To determine the extent of tumor excision by the radiologist in the immediate postoperative period using a hyperacute MRITimepoint: In the immediate postoperative period up to the first postoperative day