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Clinical Trials/NCT02773303
NCT02773303
Completed
N/A

Neurofeedback Therapy for Children Diagnosed With Autism

Carrick Institute for Graduate Studies1 site in 1 country83 target enrollmentMay 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Autism Spectrum Disorder
Sponsor
Carrick Institute for Graduate Studies
Enrollment
83
Locations
1
Primary Endpoint
Changes in qEEG
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This project aims:

  • to further explore the effectiveness of a novel sonified Neurofeedback management therapy for children diagnosed with Autism Spectrum Disorder (ASD)
  • to determine if balance control is different before and after therapy

Detailed Description

Once the informed consent of a parent or guardian has been secured, each child will be asked to provide informed assent. If the child elects to participate in the research project, he/she is enrolled in the study and assign to one of two groups: Active Comparator or Sham Comparator. If possible, his/her ability to maintain balance is then assessed using a standard extended mCTSIB protocol (standing for 25 seconds on a hard surface/4" tall foam cushion with eyes open/closed and head neutral/turned right/left/flexed or extended) and his/her baseline qEEG are recorded. A series of questionnaires will be administered to the child and/or his/her parents/legal guardian/caretaker. Afterward the child will be instructed to wear the prescribed device (either the Active Comparator (Mente Autism™) or the Sham Comparator (a device externally identical to Mente Autism™, providing binaural beats but not tailor-made neurofeedback binaural beats)) to use at home for 40 minutes a day for 12 weeks. At the end of the 12 weeks treatment period, the child will again be tested as at the beginning of the trial (posturography, qEEG, and questionnaires). At the end of the study, participants in the Sham Comparator group will be offered the option of receiving the full therapy.

Registry
clinicaltrials.gov
Start Date
May 2016
End Date
December 13, 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Carrick Institute for Graduate Studies
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • a clear diagnosis of ASD and a high starting delta wave level, as confirmed by the initial qEEG.
  • Furthermore, since the therapy is administered via a device requiring to be connected to a computer, tablet or phone with WiFi capabilities to work, the following are additional requirement:
  • iPhone 4s or later or all iPads except first generation iPAD running OS v7 or later, or
  • computer running Windows 7 or later
  • Tablet running Android 4.1 or later
  • Internet connection

Exclusion Criteria

  • a history of hearing impairment and co-morbidities such as Rett-Syndrome and if they get low delta wave recordings in frontal lobe with qEEG (part of the baseline testing battery)

Outcomes

Primary Outcomes

Changes in qEEG

Time Frame: Baseline and at week 12

Changes will be assessed between baseline (at enrollment) and after the treatment period. It will be used to investigate if Mente Autism™ therapy affect it and how much.

Secondary Outcomes

  • Changes in Stability Score(Baseline and at week 12)
  • Changes in Social Responsiveness Scale (Second Edition) SRS-2(Baseline and at week 12)
  • Changes in Autism Behaviour Checklist (ABC)(Baseline and at week 12)
  • The Behavior Rating Inventory of Executive Function (BRIEF)(Baseline and at week 12)
  • Changes in Questions about Behavioural Function (QABF) test(Baseline and at week 12)

Study Sites (1)

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