An assessment about the effect of Pregabaline(75 mg) or Deuloxetin(30 mg) on pain relief in CPD due to Endometriosis
Phase 2
Recruiting
- Conditions
- Inflammatory disease of uterus, except cervix.Chronic inflammatory disease of uterus
- Registration Number
- IRCT2015042916325N2
- Lead Sponsor
- Vice Chancellor for Research-Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
Inclusion Criteria: Known case of Endometriosis according to pathology or radiology; Pelvic pain more than 6 month; Age between 18 and 60 years old; Comprehension and sign the consent inform.
Exclusion Criteria
Previous surgery; Need to strong opioids; coexisting pelvic disorders; History of urinary tract infection,IBS, IBD, and cancer; Pregnancy and breast feeding; Psychiatric disorders(Minor and Major Depression, suicide, Bipolar disorders; Epilepsy; Hypertension; Hypersensitivity to drugs; MAOI consumption; Closed angle Glocoma; Renal Disorders; History of Juindice or hepatic disorders; Consumption of MAOI, SMRIs, SSRIs 2 weeks ago; Alcohol consumption; Hyponatremia; Weight gain>285 Pound
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain Score of Chronic pelvic pain due to Endometriosis. Timepoint: 2 weeks, 1 month, and 3 months after receiving the first dose of drug. Method of measurement: Numerical Rating Scale(NRS).
- Secondary Outcome Measures
Name Time Method Severity of Chronic pelvic pain due to Endometriosis. Timepoint: 2 weeks, 1 month, and 3 months after receiving the first dose of drug. Method of measurement: With the question: How much do you experience pain relief after receiving treatment from our center? (0-100%).