Behavioral Interventions for Chronic Pain and Opioid-Related Problems
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 95
- 试验地点
- 2
- 主要终点
- Change in pain symptoms
研究概览
简要总结
The purpose of this study is to examine the effects of Mindfulness-Oriented Recovery Enhancement versus a social support group (supportive counseling) intervention for chronic pain patients receiving long-term opioid pharmacotherapy for pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-60+
- •Current chronic pain condition
- •Current use of prescription opioid agonist or mixed agonist-antagonist analgesics for >90 days
排除标准
- •Prior experience with Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, or Mindfulness-Based Relapse Prevention
- •Active suicidality, schizophrenia, psychotic disorder, and/or severe substance dependence (other than opioid dependence)
- •Opioid misuse as determined by Current Opioid Misuse Measure
结局指标
主要结局
Change in pain symptoms
时间窗: Change from baseline through study completion (9 months post-treatment)
Pain severity and interference as measured by the Brief Pain Inventory
Change in aberrant drug-related behaviors
时间窗: Change from baseline through study completion (9 months post-treatment)
Aberrant drug-related behaviors as evidenced by triangulated aggregate of Current Opioid Misuse Measure and/or clinician assessment via Addiction Behaviors Checklist and/or urine screen
次要结局
- Change in opioid craving(Change from baseline through study completion (9 months post-treatment))
- Change in interoceptive awareness(Change from baseline through 8 weeks)
- Change in emotional distress(Change from baseline through study completion (9 months post-treatment))
- Change in opioid dose(Change from baseline through study completion (9 months post-treatment))
- Change in savoring(Change from baseline through 8 weeks)
- Change in meditative experiences(Change from baseline through 8 weeks)
- Change in reappraisal(Change from baseline through 8 weeks)
- Change in body sensations(Change from baseline through 8 weeks)
研究者
Eric Garland
Professor
University of Utah