CTRI/2021/03/032199尚未招募3 期
Pirfenidone for coronavirus disease 2019 (COVID-19) related pulmonary fibrosis: A placebo-controlled randomized controlled trial
Anant Mohan0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. History of COVID-19 illness diagnosed by RT-PCR/Rapid antigen/ Truenaat of throat or nasopharyngeal swab at least 8 weeks prior
- •2. Having persistent respiratory symptoms (cough and breathlessness) or persistent hypoxemia (SpO2 <94% on room air) or oxygen desaturation on exercise
- •Has evidence of pulmonary fibrosis on HRCT thorax (at least 15% involvement by visual semi-quantitative assessment) performed at least 8 weeks after COVID-19 diagnosis
- •3. Provides written informed consent for evaluation and treatment as per study protocol
排除标准
- •1. Patients not providing consent for participation in the study
- •2. FEV1/FVC ratio < 0.80
- •3. Active smokers
- •4. Any active malignancy/ malignancy within past 2 years
- •5. Severe hepatic impairment
- •6. Use of immunosuppressant drugs (except corticosteroids and tocilizumab) within last 6 weeks
研究者
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