Vitamin D, Hashimato's Thyroiditis and Thyroid Functions

Completed

• Conditions: Vitamin D; Thyroid Autoimmune Disease

• Registration Number: NCT06726967
• Lead Sponsor: Ankara Yildirim Beyazıt University

Brief Summary

The goal of this retrospective observational study is to determine whether vitamin D levels differ in patients with Hashimoto's thyroiditis (HT) compared to those without Hashimoto's thyroiditis. The main research questions are:

Are vitamin D levels lower in HT patients compared to non-HT patients? Do vitamin D levels vary between HT and non-HT patients based on thyroid function status?

The study was conducted by retrospectively reviewing the medical records of patients who visited the hospital outpatient clinic.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-02-01
• Primary Completion: 2024-01-01
• Study Completion: 2024-01-01
• Status Verified: 2024-12
• Study First Submitted: 2024-12-05
• Study First Submitted QC: 2024-12-05
• Last Update Submitted: 2024-12-05
• Study First Posted: 2024-12-10
• Last Update Posted: 2024-12-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 81180

Inclusion Criteria

Patients with the following biochemical parameters:

• Vitamin D (25(OH)D) levels
• Thyroid-stimulating hormone (TSH) levels
• Free triiodothyronine (fT3) levels
• Free thyroxine (fT4) levels
• Anti-thyroid peroxidase (anti-TPO) levels
• Anti-thyroglobulin (anti-Tg) levels

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anti-thyroid peroxidase (anti-TPO)	Baseline	IU/mL
anti-thyroglobulin (anti-TG)	Baseline	IU/mL
Vitamin D 25 OH D	Baseline	nmol/L
thyroid-stimulating hormone (TSH)	Baseline	uIU/mL
free thyroxine (fT4)	Baseline	ng/dL

Secondary Outcome Measures

Name	Time	Method
free triiodothyronine (fT3)	Baseline	pg/ml

Trial Locations

Locations (1)

Ankara Bilkent City Hospital; 🇹🇷 Ankara, Çankaya, Turkey