Effect of Yoga on Mood and Quality of Life in Patients With Refractory Epilepsy

University of Kansas Medical Center1 site in 1 country3 target enrollmentDecember 2016

ConditionsDepression Anxiety

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Depression
Sponsor: University of Kansas Medical Center
Enrollment: 3
Locations: 1
Primary Endpoint: Change in Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to learn if a structured yoga program can reduce anxiety, improve depression, and improve quality of life in patients with medication resistant epilepsy (MRE).

Registry

clinicaltrials.gov

Start Date

December 2016

End Date

October 4, 2017

Last Updated

8 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

University of Kansas Medical Center

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Diagnosis of unilateral or bilateral temporal lobe epilepsy
•Presence 3 or more seizures per month
•No medical contraindications to yoga
•Willing and able to perform simple non strenuous yoga exercises
•Ability to get on the floor and up again without assistance
•Ambulatory
•Ability to travel to the yoga class twice a week

Exclusion Criteria

•Any yoga in the last 6 months
•Inability to perform yoga exercises
•History of epilepsy surgery within the last year
•Currently pregnant or less than 6 week postpartum

Outcomes

Primary Outcomes

Change in Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)

Time Frame: Change from Week 4 to Week 12

The NDDI-E is a 6 item questionnaire. Scores for each question range from 1 (never) to 4 (all the time). There is a maximum score of 24. The higher the score the more severe the depression.

Secondary Outcomes

Change in Generalized Anxiety Disorder 7-item (GAD-7) scale(Change from Week 4 to Week 12)
Change in Quality of Life in Epilepsy-Patient-Weighted (QOLIE-31-p)(Change from Baseline to Week 12)
Frequency of seizures(Week 12)