Oral steroids for the treatment of inflammatory CRPS-1
- Conditions
- complex regional pain syndrome type-1
- Registration Number
- NL-OMON27326
- Lead Sponsor
- Ainvestigator initiated research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 52
Inclusion Criteria
1.CRPS-1 (clinical Budapest criteria) in one arm only.
2.Inflammatory type: painful upper extremity, temperature difference, swelling, red
discoloration, limited hand function.
Exclusion Criteria
1.Not able to comply with follow up visits
2.< 18 or > 80 years of age
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary Objective: <br><br /><br /><br>Assessment of a group difference in clinically important improvement in functional outcome of at least 10 points as measured by the DASH questionnaire<br>
- Secondary Outcome Measures
Name Time Method Secondary Objective(s): <br /><br /><br><br>1.To determine if there is a group difference in improvement in global perceive effect of therapy as measured on a 7 point scale<br /><br>2.To determine if there is a group difference in improvement in pain intensity scores as measured by a pain diary three times daily during the week before each study visit.<br /><br>3.To determine if there is a group difference in improvement in edema as measured by a measurement tape<br /><br>4.To determine if there is a group difference in improvement in discoloration as measured on a 3 point scale<br /><br>5.To determine if there is a group difference in cortisol levels of responders to treatment versus non responders. A responder is a subject who has at least 10 points improvement in the DASH questionnaire <br><br>