Obstructive Sleep Apnoea in Adolescents With Thoracic Aortic Aneurysm
Completed
- Conditions
- Thoracic Aortic Aneurysm Without RuptureObstructive Sleep Apnea
- Registration Number
- NCT03400319
- Lead Sponsor
- University of Zurich
- Brief Summary
The objective of this prospective cohort study is to determine the prevalence of obstructive sleep apnoea (OSA) in patients with and without thoracic aortic aneurysm.
- Detailed Description
The objective of this prospective cohort study is to determine the prevalence of obstructive sleep apnoea (OSA) in patients with and without thoracic aortic aneurysm.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 174
Inclusion Criteria
- Age > 18 years.
- Diagnosis of thoracic aortic aneurysm defined by the following parameters:
Women: at the level of the sinus of valsalva ≥39mm, or ascending aorta ≥42mm. (for controls: <39mm and <42mm respectively); Men: at the level of the sinus of valsalva ≥44mm, or ascending aorta ≥46mm. (for controls: <44mm and <46mm respectively)
Exclusion Criteria
- Patients on continuous positive airway pressure (CPAP) therapy for OSA at baseline.
- Patients with known central sleep apnoea.
- Patients on morphine or other opioid medication, heroin addiction, alcohol addiction.
- Patients with moderate or severe aortic regurgitation.
- Patients with moderate or severe aortic stenosis.
- Pregnant patients.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of Obstructive Sleep Apnea Baseline Prevalence of Obstructive Sleep Apnea according to a Sleep study (The ApneaLink™)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Zurich, Pulmonary Division
🇨🇭Zurich, Switzerland