Efficacy of Bupivacaine Alone and Bupivacaine With Tramadol in Local Anesthesia Procedures
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Mean postoperative pain score
研究概览
简要总结
This study looked at two different medicines used during local anesthesia to control pain after surgery. Investigators compared bupivacaine alone with bupivacaine mixed with tramadol. Both medicines are commonly used to numb the surgical area and reduce pain.
The investigators included 100 adult patients who had minor surgeries under local anesthesia. Half received only bupivacaine, and the other half received bupivacaine combined with tramadol. After surgery, patients were asked to rate their pain at 4, 8, and 24 hours.
The results showed that patients who received bupivacaine with tramadol felt less pain, especially at 24 hours after surgery, compared to those who received bupivacaine alone.
In simple words:
Adding tramadol to bupivacaine helps reduce pain better than bupivacaine alone.
This method may help patients recover faster, feel more comfortable, and need fewer pain medicines after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients undergoing elective procedure under local anesthesia
- •Either gender.
- •Age 18-60 years.
排除标准
- •Procedures Under general anesthesia.
- •Diabetic patients, assessed by history and clinically and HbA1c >6.5%
- •Patients with metastatic disease, assessed by history, clinically and by imaging.
- •Patients who are I/V opioid abusers will be excluded.
研究组 & 干预措施
Use of Bupivacaine alone for treating postoperative pain
干预措施: Bupivacaine (Drug)
Use of Bupivacaine and Tramadol together for treating postoperative pain
干预措施: Tramadol (Drug)
Use of Bupivacaine and Tramadol together for treating postoperative pain
干预措施: Bupivacaine (Drug)
结局指标
主要结局
Mean postoperative pain score
时间窗: Patients were monitored for 24 hours immediately following the completion of the surgical procedure
Mean postoperative pain score using the visual analog scale at 4,8 and 24 hours postoperatively. Visual Analog Scale (VAS) is a 10-cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain). Patients will mark the point representing their pain intensity. Scores will be recorded at predetermined postoperative intervals.
次要结局
未报告次要终点
研究者
Syeda Zareen Raza
Assistant Professor
Jinnah Postgraduate Medical Centre