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临床试验/NCT07317180
NCT07317180尚未招募不适用

The Use of Meta AI Glasses With Be My Eyes Network to Improve Mobility in Patients With Low Vision

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's0 个研究点目标入组 50 人开始时间: 2026年2月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
主要终点
patient-reported vision-targeted quality of life

研究概览

简要总结

Visual impairment, particularly from glaucoma and retinal dystrophies, significantly hinders mobility and increases the risk of falls, leading to decreased independence and mental health challenges. Current low-vision assistive technologies primarily focus on near-task magnification for reading, leaving a critical gap in tools designed to assist with real-world navigation and peripheral vision loss. To address this, the proposed research evaluates Meta AI glasses, which offer real-time scene narration and object recognition, integrated with the Be My Eyes network. The study hypothesizes that this wearable AI technology will improve ambulation, orientation, and overall quality of life for patients, providing a functional solution for mobility that traditional devices lack.

详细描述

Background

Visual impairment, including both low vision and blindness, ranks among the 10 most prevalent causes of disability in North America1. Glaucoma causes irreversible vision loss, and treatments are only available to prevent disease onset and progression, but no cure is available.2. Patients with vision loss have impairments in both physical and mental health, thus limiting their activities of daily living (ADLs).3 In turn, these patients exhibit a decreased quality of life which can result in lowered self-esteem and depression.4,5 In patients with glaucoma, functional loss often begins with glare sensitivity, mobility and difficulty ambulating.5 Due to decreased peripheral vision, patients tend to have an increased risk of accidents and falls. One study found that glaucoma patients walked up to 10% slower than those without glaucoma4. In turn, these patients experienced almost twice as many bumps, stumbles and orientation issues as compared to non-glaucomatous patients.6

Low visual acuity significantly impairs mobility in patients with retinal dystrophies, as it reduces the ability to detect obstacles, navigate unfamiliar environments, and maintain safe ambulation, especially under variable lighting conditions. Performance-based assessments such as the multi-luminance mobility test (MLMT) demonstrate that reduced visual acuity, along with diminished visual field and contrast sensitivity, correlates with slower travel speed, increased collisions, and greater difficulty in orientation and navigation tasks in real-world settings.7,8

Rationale for the Proposed Research

Although a range of low-vision devices is currently available, none are explicitly designed to address mobility as a primary functional outcome. Existing technologies largely target near tasks through optical magnification, providing support for seated reading but offering limited benefit for individuals whose major challenges stem from peripheral visual field loss or real-world navigation difficulties, an unmet need in patients with glaucoma and many inherited retinal disorders.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Supportive Care
盲法
Double (Investigator, Outcomes Assessor)

入排标准

性别
All
接受健康志愿者

入选标准

  • Confirmed diagnosis of glaucoma, retinal dystrophy, or another condition associated with legal blindness.
  • Presence of documented irreversible vision loss
  • No surgical or laser procedures in the last 6 months
  • Visual field worse than 12db or poor visual acuity 20/400 or worse

排除标准

  • Has no access to telephone
  • Unable to speak English
  • Has previously received comprehensive low vision services
  • 5. Has history of stroke with aphasia
  • Has other health condition that would preclude follow-up (e.g., significant malignancy or life-threatening disease)
  • Is unable or unwilling to attend clinic visits required for the study
  • Reports significant loss of vision since last eye exam

结局指标

主要结局

patient-reported vision-targeted quality of life

时间窗: 4 weeks

The primary outcome will be change in patient-reported vision-targeted quality of life, measured using the National Eye Institute Visual Function Questionnaire - 25 item (NEI VFQ-25).

次要结局

未报告次要终点

研究者

发起方
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
申办方类型
Other
责任方
Principal Investigator
主要研究者

Monali Malvankar

Assistant Professor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

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