Probiotics for patients with cancers
Not Applicable
- Conditions
- Health Condition 1: D759- Disease of blood and blood-formingorgans, unspecified
- Registration Number
- CTRI/2021/03/032021
- Lead Sponsor
- Christian Medical College Vellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Age >18 years.
2) Undergoing Allogenic Stem cell transplant in the Department of Haematology, CMC Vellore. 3) Presence of CRO or ESBL organism in Pre-transplant Fecal surveillance
Exclusion Criteria
1) Age <18 years
2) Susceptible organisms in the Pre-transplant Faecal surveillance.
3) Patients who already have an ongoing bacterial infection at the time of HSCT.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of Gram negative bacteraemia and culture negative sepsis, for a period of 180 days after HSCT.Timepoint: 180 days
- Secondary Outcome Measures
Name Time Method 1) Incidence of bacteraemia (gram positive and gram negative). <br/ ><br>2) All-cause mortality at days- 30, 60, 90- and 180-days post HSCT. <br/ ><br>3) Incidence of graft versus host disease. <br/ ><br>4) Incidence of Clostridium difficile infection (CDI). <br/ ><br>5) Incidence of lactobacillus bacteraemiaTimepoint: 30, 60, 90- and 180-days