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The effect of intermittent fasting on body weight and metabolic risk factors

Not Applicable
Completed
Conditions
Endocrine, nutritional and metabolic diseases
Registration Number
KCT0005930
Lead Sponsor
The Catholic University of Korea
Brief Summary

A total of 33 young adults completed the 8h TRE for 4 weeks. Participants experienced significant changes in body weight (-1.0 ± 1.4 kg), body mass index (-0.4 ± 0.5 kg/m2), and body fat (-0.4 ± 1.9%) after 4 weeks of TRE. When participants were divided into weight loss/gain groups based on their weight change in week 4, fat mass reduction was significantly higher in the weight loss group than in the weight gain group. Regarding cardiometabolic risk factors, levels of fasting insulin and insulin resistance improved in the weight loss group after intervention, but not in the weight gain group. All subjects showed late-shifted sleeping patterns, but no significant differences in sleep duration, sleep quality, or psychological measures between the two groups. When meal frequency and energy proportion were evaluated, the average meal frequency was 2.8 ± 0.5 and energy proportions of breakfast, lunch, dinner, and snacks were 4.5, 39.2, 37.6, and 18.5%, respectively; there were no significant differences between the two groups. However, the saturated fat intake at dinner was lower in the weight loss group (3.1 ± 3.2%, 6.0 ± 2.5% respectively). In conclusion, an 8h TRE can be used as a lifestyle strategy in the management of body weight and cardiometabolic risk factors among healthy young adults.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
33
Inclusion Criteria

Adults aged 18-30 years old who can faithfully perform 4-week meal interventions without specific metabolic disease

Exclusion Criteria

1) Subjects who have a history of metabolic disease and who are currently taking drugs (metabolic diseases include diabetes, dyslipidemia, metabolic syndrome), 2) those who gained or lost weight in the last month (more than 10% of their existing weight), 3) Those who cannot secure normal sleep time due to part-time work or outside routine

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
body weight;blood lipids;fasting blood glucose;serum insulin
Secondary Outcome Measures
NameTimeMethod
Sleep quality variables;psychometric variables;dietary intake
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