ACTRN12620000991910
Terminated
未知
Double-blind, placebo-controlled, cross-over trial of LivauxTM for the treatment of constipation and microbiome restoration in Parkinson’s disease.
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Parkinson's Disease
- Sponsor
- The University of Queensland
- Enrollment
- 14
- Status
- Terminated
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Diagnosis of Parkinson’s disease according to UK Parkinson’s Disease Society Brain Bank Diagnostic Criteria
- •2\.Currently meet ROME IV criteria for functional constipation
- •3\.Experience 3 or fewer bowel motion days per week
- •4\.18 years or older
- •5\.BMI range 19\-35
- •6\.Prepared to maintain current dietary habits for the duration of the study
Exclusion Criteria
- •1\.Allergy to Kiwifruit
- •2\.Allergy to latex
- •3\.Clinically significant (as defined by local PI) gastrointestinal disorders not limited to:
- •Inflammatory Bowel Disease
- •History of major GI surgery
- •Structural or metabolic diseases affecting GI system
- •4\.Other identifiable cause of constipation such as other neurological diseases, peripheral neuropathy, iatragenic constipation
- •5\.Clinically significant or respiratory, cardiac failure or other concurrent medical conditions as defined by local PI
- •6\.Current or recent use (within 2 weeks of baseline) of probiotics including
- •Probiotic yoghurt or probiotic yoghurt drinks,
Outcomes
Primary Outcomes
Not specified
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